One of our most downloaded episodes is back.

If you've been diagnosed with histamine intolerance, MCAS, or unexplained food sensitivities, this replay is one you won't want to miss.

In this listener-favorite episode, Joanne Kennedy explains why histamine intolerance is not a diagnosis—it's a symptom of deeper underlying health issues. While many people rely on a low histamine diet to manage symptoms, lasting improvement comes from identifying and treating the root causes driving excess histamine production.

Drawing on years of clinical experience, Joanne walks through the most common contributors to histamine intolerance, including SIBO, gut dysbiosis, leaky gut, digestive enzyme insufficiency, mold illness, oxalates, methylation issues, hormonal imbalances, and chronic inflammation.

Whether you're a practitioner, student, or someone struggling with chronic histamine symptoms, this episode will help you better understand why histamine intolerance develops—and where to start looking for answers.

Listen, Learn & Share

If this episode helps you better understand your histamine symptoms, please follow The Histamine Well Podcast, leave a review, and share it with someone searching for answers.

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📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

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