Tonight, a complete change of course for Britain's most famous royal exiles. The Duke and Duchess of Sussex-- Prince Harry and Meghan-- and their two young children, are ending six years of self-imposed exile from the U.K. and their royal duties, announcing they are planning to move back to Britain. Plus, what appears to be some of the most promising news in a long time in the war on cancer. A new vaccine that can be tailor-made to fight an especially aggressive, and deadly form of skin cancer.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

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