Jay Bhattacharya returns to GoodFellows—now as NIH director and acting CDC director—for a candid conversation on what COVID got wrong, why science needs a replication revolution, and how to restore public trust. Jay takes on the legacy of lockdowns, school closures, Fauci, gain-of-function research, China, AI-enabled biosecurity risks, vaccine questions, and the fight to make scientific dissent possible again.

Then: Iran, the Strait of Hormuz, AI guardrails, democratic socialism, and what Homer can still teach us about war.

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