Karen Rodriguez has appeared on a handful of popular shows, but in just a few years, she’s found herself right smack in the middle of two of the biggest hits as a series regular. First came Netflix’s The Hunting Wives, the series adaptation of May Cobb’s hugely popular novel. Whereas headliners like Brittany Snow and Malin Akerman are leaning into the extremes of the characters' situation — and to great effect — Rodriguez tackles the task of serving as the show’s grounded heart, Deputy Wanda Salazar. Rodriguez made such a big impression doing that that she was made a series regular for the second season, which is due out in the fall.
While you wait for more Hunting Wives, you can catch Rodriguez in one of the most highly anticipated new superhero projects of 2026, Prime Video’s Spider-Noir. Rodriguez stars opposite Nicolas Cage’s Ben Reilly as Janet Ruiz, his trusty secretary and fellow investigator. Ben may be the one with the superpowers, fighting crime in New York City as The Spider, but it’s Janet's intuition that helps them connect with clients, often sparking the groundbreaking level of understanding needed to crack a case.
With all eight episodes of Spider-Noir now available to stream on Prime Video, in Black & White and also True-Hue color, Rodriguez visited the Collider Ladies Night studio to revisit her journey to Netflix, discuss what it was like scoring her very first series regular role in Spider-Noir, and to dig into how Janet is Reilly Investigations secret weapon.
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